Development of Rapid and Efficient Diagnostic Platforms for the Detection of Emerging Viruses in KSA

This research program is structured to address all aspects of viruses sensing technologies, starting from the fundamental concepts and culminating in practical solutions and implementations. Our efforts will focus on the development of rapid screening sensors and assays in the field and doctor offices and confirmation assays.

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Evaluation of Eukaryote

Made Thermostable DNA Polymerase to Expedite Inhouse and Point of Care COVID-19 RT-PCR Test kits Manufacturing

One of the main objectives of the proposed study is to develop eukaryote-made thermostable DNA (Taq) polymerase to achieve the production of Taq polymerase free from bacterial DNA contamination which would result in lower false positive results from contaminating bacterial DNA. The second main objective of the study is to establish an inhouse molecular diagnostic method using inhouse viral RNA isolation and SARS-CoV-2 rRT-PCR assays utilizing the eukaryote made Taq polymerase to enhance the sensitivity of the detection and provide cheaper alternative to the expensive kits currently available for SARS-CoV-2 detection.


Finite Element in Biomedical Structural Applications

Finite element method has been used to simulate Traumatic Brain Injury. Solid model of the head was created from CT-Scan images which is incorporated in finite element simulation software to investigate stress wave propagation in the skull and the brain tissues. By understanding the state of stress, strain and the magnitude of acceleration in the brain tissues when subject to TBI, we can come up with an innovative nature inspired design of helmets that can reduce the severity of impact wave on the brain.

We attempt to develop a finite element model that predicts tooth movement under orthodontic loading and that takes into account the interaction between adjacent teeth. A 3D model was constructed from CBCT scan and introduced to finite element simulation tool. Recommendations on the drection and magnitude of the movement force can be made to reduce the treatment duration and to lessen patients’ discomfort